Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.66 |
| ▸ | RAB9A | P51151 | 5/20 | 0.66 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | RARB | P10826 | 5/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090549 | 0.97 | NPC1 (0.66) | NPC1RAB9ANR1H4PKMRARB | |
| SCHEMBL7323408 | 0.90 | RARB (0.75) | NPC1RAB9ANR1H4RARBTP53 | |
| SCHEMBL7323297 | 0.89 | RARB (0.70) | NPC1RAB9ANR1H4RARBTP53 | |
| SCHEMBL7323524 | 0.88 | NR1H4 (0.64) | NPC1RAB9ANR1H4RARBTP53 | |
| SCHEMBL7314596 | 0.88 | RARB (0.78) | NPC1RAB9ANR1H4RARBTP53 | |
| SCHEMBL8087307 | 0.88 | RARB (0.78) | NPC1RAB9ANR1H4RARBTP53 | |
| SCHEMBL12171578 | 0.88 | NR1H4 (0.70) | NPC1RAB9ANR1H4RARBTP53 | |
| SCHEMBL7321777 | 0.87 | MAPT (0.64) | NPC1RAB9ANR1H4TP53KDM4E | |
| SCHEMBL5640122 | 0.87 | NPC1 (0.56) | NPC1RAB9ANR1H4PKMRARB | |
| SCHEMBL7315727 | 0.87 | PKM (0.79) | PKMRARBTP53ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |
| EP-1053247-A1 | ANTIFUNGAL CYCLOHEXAPEPTIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999040108-A1 | NEW COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-12 | — | — | WO | disclosed |