Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323166 | 0.91 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1MTNR1AMTNR1B | |
| SCHEMBL7317804 | 0.89 | KMT2A (0.54) | MEN1KMT2AALDH1A1MTNR1AMAPT | |
| SCHEMBL7323187 | 0.89 | MTNR1A (0.48) | MEN1KMT2AALDH1A1MTNR1AMAPT | |
| SCHEMBL7322098 | 0.86 | MTNR1A (0.48) | MEN1KMT2AMTNR1AMAPTPOLB | |
| SCHEMBL7321080 | 0.85 | MAPT (0.45) | MEN1KMT2AMTNR1AMAPTPOLB | |
| SCHEMBL7317547 | 0.84 | MEN1 (0.42) | MEN1KMT2AALDH1A1MTNR1AMTNR1B | |
| SCHEMBL7324219 | 0.83 | MEN1 (0.42) | MEN1KMT2AALDH1A1MTNR1AMTNR1B | |
| SCHEMBL7321962 | 0.82 | HSP90AA1 (0.47) | MEN1KMT2AALDH1A1MTNR1AMTNR1B | |
| SCHEMBL7317479 | 0.82 | TP53 (0.47) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7317380 | 0.82 | TP53 (0.47) | MEN1KMT2AALDH1A1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929097-A | INHIBIT TUMOR NECROSIS FACTOR-ALPHA CONVERTING ENZYME | AMERICAN CYANAMID COMPANY (US) | 1999-07-27 | — | — | US | disclosed |