Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2919972 | 0.85 | SMN1; SMN2 (0.82) | SMN1; SMN2LMNAHPGDKMT2ABRD4 | |
| SCHEMBL9875462 | 0.75 | KMT2A (0.61) | SMN1; SMN2KMT2ABRD4MAPK1L3MBTL1 | |
| SCHEMBL24162968 | 0.74 | HPGD (0.70) | SMN1; SMN2LMNAHPGDKMT2AALDH1A1 | |
| SCHEMBL6848908 | 0.74 | SMN1; SMN2 (0.66) | SMN1; SMN2LMNAHPGDKMT2ABRD4 | |
| SCHEMBL9543614 | 0.73 | MEN1 (0.67) | SMN1; SMN2LMNAHPGDKMT2AALDH1A1 | |
| SCHEMBL10949279 | 0.73 | ALDH1A1 (0.69) | SMN1; SMN2LMNAHPGDKMT2AALDH1A1 | |
| SCHEMBL4738279 | 0.71 | DUSP3 (0.71) | SMN1; SMN2LMNAHPGDKMT2AALDH1A1 | |
| SCHEMBL28859140 | 0.71 | NR1H4 (0.82) | SMN1; SMN2LMNAHPGDALDH1A1L3MBTL1 | |
| SCHEMBL11639395 | 0.71 | ALDH1A1 (0.61) | SMN1; SMN2LMNAHPGDKMT2ABRD4 | |
| SCHEMBL2926787 | 0.71 | ALDH1A1 (0.78) | SMN1; SMN2LMNAHPGDKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0293925-A2 | Compound active in cardiovascular therapy | SIMES, SOCIETA ITALIANA MEDICINALI E SINTETICI, S.P.A. (IT) | 1988-12-07 | — | — | EP | disclosed |