Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8947318 | 0.80 | KMT2A (0.67) | KMT2AMEN1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL4147862 | 0.79 | KMT2A (0.71) | KMT2AMEN1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL8599574 | 0.79 | KMT2A (0.71) | KMT2AMEN1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL2451128 | 0.79 | ALDH1A1 (0.66) | KMT2AMEN1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL16232794 | 0.78 | KMT2A (0.69) | KMT2AMEN1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL13922753 | 0.78 | KMT2A (0.69) | KMT2AMEN1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL7952955 | 0.78 | KMT2A (0.69) | KMT2AMEN1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL11373983 | 0.78 | KMT2A (0.69) | KMT2AMEN1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL9543614 | 0.76 | MEN1 (0.67) | KMT2AMEN1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL2926341 | 0.76 | KMT2A (0.77) | KMT2AMEN1MAPK1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983606-A | Pharmaceutically-active phthalazine compounds | ZAMBON GROUP S.P.A. (IT) | 1991-01-08 | — | — | US | disclosed |