Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | FURIN | P09958 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 14/20 | 0.44 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7332586 | 0.81 | PRSS1 (0.59) | F2F10PRSS1PLGPLAU | |
| SCHEMBL324485 | 0.81 | ESRRA (0.47) | STS | |
| SCHEMBL6589293 | 0.81 | TSHR (0.52) | — | |
| SCHEMBL7332931 | 0.79 | PLAU (0.40) | F2PRSS1PLGPLAUKLK1 | |
| Hydrochloric Acid SCHEMBL6291825 | 0.77 | PRSS1 (0.59) | F2F10FURINPRSS1PLG | |
| SCHEMBL7329837 | 0.77 | PRSS1 (0.63) | F10PRSS1TMPRSS15PRSS2PRSS3 | |
| SCHEMBL7326867 | 0.77 | KDM4E (0.43) | F2PRSS1PLGPLAUKLK1 | |
| SCHEMBL323143 | 0.76 | GSK3B (0.45) | STS | |
| SCHEMBL7323721 | 0.76 | TMPRSS15 (0.54) | F2F10PRSS1TMPRSS15KLK1 | |
| SCHEMBL11453642 | 0.75 | CYP3A4 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4570006-A | ANTITHROMBIN; ENZYME AND HORMONE INHIBITORS | TORII & CO. LTD. (JP) | 1986-02-11 | — | — | US | disclosed |
| US-4514416-A | Amidine compound, process for producing same and anti-complement agent comprising same | TORII & CO. LTD. (JP) | 1985-04-30 | — | — | US | disclosed |