SCHEMBL7323618

SCHEMBL7323618

CCOC(=O)[C@@H](O)CNC(=O)C1(CC(CCc2ccccc2)C(=O)O)CCCC1

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MME P08473 19/20 0.55
MMP1 P03956 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7319319 1.00 MME (0.55) MMEMMP1
SCHEMBL7327458 0.90 MME (0.45) MMEMMP1
SCHEMBL391627 0.88 MME (0.56) MMEMMP1
SCHEMBL7321471 0.79 MME (0.52) MMEMMP1
SCHEMBL9226790 0.79 MME (0.52) MMEMMP1
SCHEMBL7315624 0.79 MME (0.52) MMEMMP1
SCHEMBL8894558 0.78 MME (0.48) MME
SCHEMBL8733280 0.78 MME (0.48) MME
SCHEMBL7446467 0.76 MME (0.55) MMEMMP1
SCHEMBL7326831 0.76 MME (0.50) MMEMMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5389610-A For cardiovascular disorders SCHERING CORPORATION (US) 1995-02-14 US claimed
EP-0502075-A1 CARBOXYALKYLCARBONYL AMINOACID ENDOPEPTIDASE INHIBITORS SCHERING CORPORATION (US) 1992-09-09 EP claimed
WO-1991007386-A1 CARBOXYALKYLCARBONYL AMINOACID ENDOPEPTIDASE INHIBITORS SCHERING CORPORATION (US) 1991-05-30 WO claimed