Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 17/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323618 | 0.90 | MME (0.55) | MMEMMP1 | |
| SCHEMBL7319319 | 0.90 | MME (0.55) | MMEMMP1 | |
| SCHEMBL7321839 | 0.81 | MME (0.45) | MMECTSSCTSKMMP1 | |
| SCHEMBL7326860 | 0.81 | PPID (0.44) | MMECTSSCTSK | |
| SCHEMBL7326856 | 0.81 | PPID (0.44) | MMECTSSCTSK | |
| SCHEMBL7326866 | 0.81 | PPID (0.44) | MMECTSSCTSK | |
| SCHEMBL9221373 | 0.78 | MME (0.42) | MMECTSS | |
| SCHEMBL391627 | 0.78 | MME (0.56) | MMEMMP1 | |
| SCHEMBL8894558 | 0.77 | MME (0.48) | MME | |
| SCHEMBL8733280 | 0.77 | MME (0.48) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389610-A | For cardiovascular disorders | SCHERING CORPORATION (US) | 1995-02-14 | — | — | US | disclosed |
| EP-0502075-A1 | CARBOXYALKYLCARBONYL AMINOACID ENDOPEPTIDASE INHIBITORS | SCHERING CORPORATION (US) | 1992-09-09 | — | — | EP | disclosed |
| WO-1991007386-A1 | CARBOXYALKYLCARBONYL AMINOACID ENDOPEPTIDASE INHIBITORS | SCHERING CORPORATION (US) | 1991-05-30 | — | — | WO | disclosed |