Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.49 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.49 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.49 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328053 | 0.84 | KMT2A (0.54) | KMT2AMEN1ALDH1A1L3MBTL1OPRM1 | |
| SCHEMBL30530478 | 0.81 | APOBEC3G (0.61) | KMT2AMEN1ALDH1A1L3MBTL1GRIA1 | |
| SCHEMBL7329647 | 0.81 | APOBEC3G (0.61) | KMT2AMEN1ALDH1A1L3MBTL1GRIA1 | |
| SCHEMBL7320509 | 0.79 | PRNP (0.58) | KMT2AMEN1ALDH1A1L3MBTL1GRIA1 | |
| SCHEMBL982104 | 0.74 | CYP1A2 (0.69) | KMT2AMEN1ALDH1A1GRIA1GRIA2 | |
| SCHEMBL29579885 | 0.74 | CYP1A2 (0.69) | KMT2AMEN1ALDH1A1GRIA1GRIA2 | |
| SCHEMBL29212230 | 0.74 | GRIA1 (0.52) | KMT2AMEN1ALDH1A1L3MBTL1OPRM1 | |
| SCHEMBL30530474 | 0.74 | GRIA1 (0.52) | KMT2AMEN1ALDH1A1L3MBTL1OPRM1 | |
| SCHEMBL7321461 | 0.73 | KDM4E (0.67) | KMT2AMEN1ALDH1A1L3MBTL1OPRM1 | |
| SCHEMBL7322530 | 0.72 | GABRA5 (0.53) | KMT2AMEN1ALDH1A1GRIA1GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075304-A | Nervous system disorders | NOVO NORDISK A/S (DK) | 1991-12-24 | — | — | US | disclosed |
| EP-0344943-A1 | Imidazoquinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1989-12-06 | — | — | EP | disclosed |