SCHEMBL7323832

SCHEMBL7323832

C=CCCC(CC)[N+](=O)[O-]

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
TSHR P16473 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5252924 0.81 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL4357367 0.80 TSHR (0.45) ALDH1A1TSHR
SCHEMBL28195500 0.78
SCHEMBL2799546 0.76
SCHEMBL1118146 0.75
Formaldehyde SCHEMBL7212866 0.74 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL1170405 0.74
SCHEMBL6380772 0.71
SCHEMBL1170561 0.71 ALDH1A1 (0.42) ALDH1A1TSHR
SCHEMBL7323835 0.71 CPA1 (0.40) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3118361-A None JP disclosed
US-5444083-A DOPAMINE AGONIST FOR TREATING OR PREVENTION OF HYPERTENSION OR HEART FAILURE EISAI CO., LTD. (JP) 1995-08-22 US disclosed
EP-0381235-B1 PYRROLIDINE COMPOUND AND PHARMACEUTICAL USE Eisai Co., Ltd. (JP) 1993-07-28 EP disclosed
JP-H03118361-A PYRROLIDINE DERIVATIVE EISAI CO LTD 1991-05-20 JP disclosed
EP-0381235-A2 Pyrrolidine compound and pharmaceutical use Eisai Co., Ltd. (JP) 1990-08-08 EP disclosed