Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 4/20 | 0.38 |
| ▸ | IDH1 | O75874 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 4/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | PLD2 | O14939 | 1/20 | 0.33 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322702 | 0.91 | PREP (0.40) | P2RX7FAAHIDH1PREP | |
| SCHEMBL7352616 | 0.86 | FAAH (0.37) | P2RX7FAAHIDH1F2GHSR | |
| SCHEMBL7316140 | 0.85 | PREP (0.45) | F2PREP | |
| SCHEMBL7320008 | 0.83 | F2 (0.43) | F2PREP | |
| SCHEMBL7323490 | 0.82 | PREP (0.46) | IDH1F2PREP | |
| SCHEMBL7331463 | 0.80 | F2 (0.40) | F2PREP | |
| SCHEMBL7322848 | 0.80 | F2 (0.40) | F2PREP | |
| SCHEMBL7324397 | 0.80 | PREP (0.47) | PREPPTGDR2 | |
| SCHEMBL7324059 | 0.80 | IDH1 (0.33) | P2RX7FAAHIDH1F2 | |
| SCHEMBL7332387 | 0.79 | IDH1 (0.34) | FAAHIDH1PLD2PLD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372484-B1 | Condensed benzene derivative | ZERIA PHARM CO LTD (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5028604-A | Cognition Activators | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0372484-A2 | Condensed benzene derivative | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-13 | — | — | EP | disclosed |