Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 11/20 | 0.61 |
| ▸ | MKNK2 | Q9HBH9 | 11/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7321701 | 1.00 | MKNK1 (0.61) | MKNK1MKNK2MAPTFYNPIK3CA | |
| SCHEMBL7318292 | 1.00 | MKNK1 (0.61) | MKNK1MKNK2MAPTFYNPIK3CA | |
| SCHEMBL7324198 | 1.00 | MKNK1 (0.61) | MKNK1MKNK2MAPTFYNPIK3CA | |
| SCHEMBL6132537 | 0.90 | MKNK1 (0.52) | MKNK1MKNK2MAPTFYNHPGD | |
| SCHEMBL6132847 | 0.90 | MKNK1 (0.51) | MKNK1MKNK2PIK3CA | |
| SCHEMBL6132243 | 0.82 | HDAC3 (0.52) | MKNK1MKNK2MAPTRAB9AHPGD | |
| SCHEMBL7319177 | 0.81 | MAPT (0.56) | MAPTRAB9AHTTSMN1; SMN2HDAC1 | |
| SCHEMBL7324575 | 0.81 | MAPT (0.56) | MAPTRAB9AHTTSMN1; SMN2HDAC1 | |
| SCHEMBL7397503 | 0.81 | MAPT (0.56) | MAPTRAB9AHTTSMN1; SMN2HDAC1 | |
| SCHEMBL6132721 | 0.81 | RARB (0.59) | MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |