Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 10/20 | 0.51 |
| ▸ | MKNK2 | Q9HBH9 | 10/20 | 0.51 |
| ▸ | RARB | P10826 | 4/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132721 | 0.92 | RARB (0.59) | MKNK1MKNK2RARBCSNK2A2CSNK2A1 | |
| SCHEMBL7326113 | 0.91 | RARB (0.55) | MKNK1MKNK2RARBCSNK2A2CSNK2A1 | |
| SCHEMBL7318292 | 0.90 | MKNK1 (0.61) | MKNK1MKNK2PIK3CA | |
| SCHEMBL7321701 | 0.90 | MKNK1 (0.61) | MKNK1MKNK2PIK3CA | |
| SCHEMBL7324612 | 0.90 | MKNK1 (0.61) | MKNK1MKNK2PIK3CA | |
| SCHEMBL7324198 | 0.90 | MKNK1 (0.61) | MKNK1MKNK2PIK3CA | |
| SCHEMBL6132537 | 0.88 | MKNK1 (0.52) | MKNK1MKNK2TSHR | |
| SCHEMBL7067920 | 0.82 | MKNK1 (0.49) | MKNK1MKNK2CSNK2A2CSNK2A1 | |
| SCHEMBL6132394 | 0.82 | MKNK1 (0.46) | MKNK1MKNK2PIK3CACSNK2A2CSNK2A1 | |
| Hydrochloric Acid SCHEMBL6133903 | 0.82 | MKNK1 (0.49) | MKNK1MKNK2CSNK2A2CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1259535-A1 | CYCLIC HEXAPEPTIDE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001060846-A1 | CYCLIC HEXAPEPTIDE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-08-23 | — | — | WO | disclosed |