Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7323995 | 0.99 | SIGMAR1 (0.42) | SIGMAR1HTR1AADRA1BSLC6A4SLC6A3 | |
| SCHEMBL8330431 | 0.88 | SIGMAR1 (0.43) | SIGMAR1HTR1AADRA1BHRH3TMEM97 | |
| SCHEMBL8330429 | 0.88 | SIGMAR1 (0.43) | SIGMAR1HTR1AADRA1BHRH3TMEM97 | |
| SCHEMBL11634999 | 0.88 | SIGMAR1 (0.51) | SIGMAR1SLC6A4SLC6A3SLC6A2HRH1 | |
| Hydrochloric Acid SCHEMBL9319984 | 0.87 | SIGMAR1 (0.50) | SIGMAR1SLC6A4SLC6A3SLC6A2HRH1 | |
| SCHEMBL7321086 | 0.84 | SIGMAR1 (0.53) | SIGMAR1SLC6A4SLC6A3SLC6A2HRH1 | |
| SCHEMBL7317122 | 0.81 | SIGMAR1 (0.52) | SIGMAR1HRH1HRH3SCN5A | |
| SCHEMBL30493951 | 0.79 | ABCB1 (0.60) | SIGMAR1SLC6A4SLC6A2HRH3KCNH2 | |
| SCHEMBL7325720 | 0.79 | ABCB1 (0.60) | SIGMAR1SLC6A4SLC6A2HRH3KCNH2 | |
| SCHEMBL7317897 | 0.78 | SIGMAR1 (0.45) | SIGMAR1HTR1AADRA1BHRH3TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0917464-A1 | USE OF AMINES TO PRODUCE DRUGS FOR PREVENTING TUMOUR CELL PROLIFERATION | SANOFI (FR) | 1999-05-26 | — | — | EP | claimed |
| WO-1998004251-A1 | USE OF AMINES TO PRODUCE DRUGS FOR PREVENTING TUMOUR CELL PROLIFERATION | SANOFI (FR) | 1998-02-05 | — | — | WO | claimed |
| US-20230364033-A1 | COMPOUNDS FOR TREATING VIRUS INFECTIONS | MELETIOS THERAPEUTICS (FR) | 2023-11-16 | — | — | US | disclosed |
| EP-4213822-A1 | COMPOUNDS FOR TREATING VIRUS INFECTIONS | MELETIOS Therapeutics (FR) | 2023-07-26 | — | — | EP | disclosed |
| CN-116437960-A | Compounds for the treatment of viral infections | 梅莱蒂奥斯治疗 | 2023-07-14 | — | — | CN | disclosed |
| WO-2022058533-A1 | COMPOUNDS FOR TREATING VIRUS INFECTIONS | MELETIOS THERAPEUTICS (FR) | 2022-03-24 | — | — | WO | disclosed |
| US-6235791-B1 | USING CIS N-CYCLOHEXYL-N-ETHYL(3-(3-CHLORO-CYCLOHEXYLPHENYL)ALLYL)AMINE | SANOFI-SYNTHELABO (FR) | 2001-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230364033-A1 | COMPOUNDS FOR TREATING VIRUS INFECTIONS | ACE, HAVCR2, FURIN | SIGMAR1 3429/4885HTR1A 4224/4885ADRA1B 2882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.