Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.43 |
| ▸ | EBP | Q15125 | 2/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | GPR183 | P32249 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8330429 | 1.00 | SIGMAR1 (0.43) | SIGMAR1EBPTMEM97HRH3HTR1A | |
| SCHEMBL30494033 | 0.89 | SIGMAR1 (0.51) | SIGMAR1EBPTMEM97HTR1AADRA1B | |
| SCHEMBL8524209 | 0.89 | SIGMAR1 (0.51) | SIGMAR1EBPTMEM97HTR1AADRA1B | |
| SCHEMBL25317113 | 0.89 | SIGMAR1 (0.51) | SIGMAR1EBPTMEM97HTR1AADRA1B | |
| SCHEMBL7317908 | 0.89 | SIGMAR1 (0.45) | SIGMAR1EBPTMEM97HRH3HTR1A | |
| SCHEMBL7317905 | 0.89 | SIGMAR1 (0.45) | SIGMAR1EBPTMEM97HRH3HTR1A | |
| SCHEMBL7317897 | 0.89 | SIGMAR1 (0.45) | SIGMAR1EBPTMEM97HRH3HTR1A | |
| Hydrochloric Acid SCHEMBL7324536 | 0.88 | SIGMAR1 (0.50) | SIGMAR1EBPTMEM97HTR1AADRA1B | |
| Hydrochloric Acid SCHEMBL7324521 | 0.88 | SIGMAR1 (0.50) | SIGMAR1EBPTMEM97HTR1AADRA1B | |
| Hydrochloric Acid SCHEMBL7324525 | 0.88 | SIGMAR1 (0.50) | SIGMAR1EBPTMEM97HTR1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0917464-A1 | USE OF AMINES TO PRODUCE DRUGS FOR PREVENTING TUMOUR CELL PROLIFERATION | SANOFI (FR) | 1999-05-26 | — | — | EP | disclosed |
| WO-1998004251-A1 | USE OF AMINES TO PRODUCE DRUGS FOR PREVENTING TUMOUR CELL PROLIFERATION | SANOFI (FR) | 1998-02-05 | — | — | WO | disclosed |