SCHEMBL7324877

SCHEMBL7324877

CCCCc1nc(COC)c(Cl)n1Cc1ccc(NC)cc1

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 1/20 0.47
AGTR2 P50052 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL301 0.84
SCHEMBL7325291 0.77 PPARG (0.57) AGTR1AGTR2
SCHEMBL9530525 0.73 AGTR1 (0.46) AGTR1AGTR2
SCHEMBL11092792 0.73 AGTR1 (0.63) AGTR1AGTR2
SCHEMBL90 0.71
SCHEMBL9585230 0.71 TLR7 (0.49) AGTR1AGTR2
SCHEMBL7317556 0.71 AGTR1 (0.58) AGTR1AGTR2
SCHEMBL7326958 0.71 AGTR1 (0.60) AGTR1AGTR2
SCHEMBL1128 0.70 AGTR1 (0.54) AGTR1AGTR2
SCHEMBL212 0.69 AGTR1 (0.79) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0253310-A2 Angiotensin II receptor blocking imidazoles E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-01-20 EP disclosed