Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.52 |
| ▸ | PSEN1 | P49768 | 7/20 | 0.51 |
| ▸ | PSEN2 | P49810 | 7/20 | 0.51 |
| ▸ | APH1B | Q8WW43 | 7/20 | 0.51 |
| ▸ | NCSTN | Q92542 | 7/20 | 0.51 |
| ▸ | APH1A | Q96BI3 | 7/20 | 0.51 |
| ▸ | PSENEN | Q9NZ42 | 7/20 | 0.51 |
| ▸ | REN | P00797 | 3/20 | 0.51 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322611 | 0.85 | KLK5 (0.58) | CTSDKMT2AMEN1ATMKLK5 | |
| SCHEMBL7330949 | 0.85 | KLK5 (0.58) | CTSDKMT2AMEN1ATMKLK5 | |
| SCHEMBL7323031 | 0.85 | KLK5 (0.58) | CTSDKMT2AMEN1ATMKLK5 | |
| SCHEMBL28961339 | 0.83 | CTSD (0.67) | CTSDKLK5PSEN1PSEN2APH1B | |
| SCHEMBL11661865 | 0.83 | CTSD (0.67) | CTSDKLK5PSEN1PSEN2APH1B | |
| SCHEMBL7330691 | 0.82 | CTSD (0.54) | CTSDKMT2AMEN1 | |
| SCHEMBL7330359 | 0.82 | ACE (0.56) | KMT2AATMCTSSCTSLCTSB | |
| SCHEMBL7330351 | 0.82 | ACE (0.56) | KMT2AATMCTSSCTSLCTSB | |
| SCHEMBL7329299 | 0.82 | ACE (0.56) | KMT2AATMCTSSCTSLCTSB | |
| SCHEMBL7331478 | 0.81 | BACE1 (0.49) | CTSDCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |