Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.56 |
| ▸ | CTSS | P25774 | 3/20 | 0.56 |
| ▸ | CTSK | P43235 | 2/20 | 0.56 |
| ▸ | CTSL | P07711 | 1/20 | 0.56 |
| ▸ | CTSB | P07858 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330351 | 1.00 | ACE (0.56) | ACECTSSCTSKCTSLCTSB | |
| SCHEMBL7329299 | 1.00 | ACE (0.56) | ACECTSSCTSKCTSLCTSB | |
| SCHEMBL7321445 | 0.98 | ACE (0.56) | ACECTSSCTSKCTSLCTSB | |
| SCHEMBL7321427 | 0.98 | ACE (0.56) | ACECTSSCTSKCTSLCTSB | |
| SCHEMBL7325133 | 0.82 | CTSD (0.57) | CTSSCTSKCTSLCTSBKMT2A | |
| SCHEMBL7357804 | 0.79 | KLK5 (0.55) | ACECTSSCTSKCTSLCTSB | |
| SCHEMBL7359025 | 0.79 | KLK5 (0.55) | ACECTSSCTSKCTSLCTSB | |
| SCHEMBL606309 | 0.79 | ACE (0.79) | ACECTSSCTSKCTSLCTSB | |
| SCHEMBL21473784 | 0.79 | ACE (0.79) | ACECTSSCTSKCTSLCTSB | |
| SCHEMBL7269746 | 0.79 | CTSS (0.70) | ACECTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |