Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5960683 | 0.82 | SMN1; SMN2 (0.67) | L3MBTL1KMT2AGAASMN1; SMN2MAPT | |
| SCHEMBL1137736 | 0.81 | L3MBTL1 (0.64) | L3MBTL1KMT2AGAASMN1; SMN2MAPT | |
| SCHEMBL407215 | 0.81 | L3MBTL1 (0.64) | L3MBTL1KMT2AGAASMN1; SMN2MAPT | |
| SCHEMBL668653 | 0.81 | L3MBTL1 (0.64) | L3MBTL1KMT2AGAASMN1; SMN2MAPT | |
| SCHEMBL8194522 | 0.81 | L3MBTL1 (0.64) | L3MBTL1KMT2AGAASMN1; SMN2MAPT | |
| SCHEMBL5943967 | 0.81 | L3MBTL1 (0.64) | L3MBTL1KMT2AGAASMN1; SMN2MAPT | |
| SCHEMBL29482636 | 0.81 | L3MBTL1 (0.64) | L3MBTL1KMT2AGAASMN1; SMN2MAPT | |
| SCHEMBL29406781 | 0.81 | L3MBTL1 (0.64) | L3MBTL1KMT2AGAASMN1; SMN2MAPT | |
| SCHEMBL30965843 | 0.81 | L3MBTL1 (0.64) | L3MBTL1KMT2AGAASMN1; SMN2MAPT | |
| SCHEMBL11327832 | 0.80 | L3MBTL1 (0.58) | L3MBTL1KMT2AGAASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5385914-A | Cardiotonic carbostyril agents for treating heart ailments | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-01-31 | — | — | US | disclosed |
| EP-0355583-B1 | Cardiotonics | OTSUKA PHARMA CO LTD (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5266577-A | Method of treating congestive heart failure using carbostyril derivatives | OTSUKA PHARMACEUTICAL COMPANY LTD. (JP) | 1993-11-30 | — | — | US | disclosed |
| US-5198448-A | Cardiovascular disorders | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1993-03-30 | — | — | US | disclosed |
| US-5053514-A | Side effect reduction; carbostyril derivatives | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1991-10-01 | — | — | US | disclosed |
| EP-0355583-A2 | Cardiotonics | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |