SCHEMBL407215

SCHEMBL407215

COc1ccc(OC)c(S(=O)(=O)Cl)c1

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.64
TP53 P04637 1/20 0.56
ALDH1A1 P00352 4/20 0.54
NPSR1 Q6W5P4 2/20 0.54
TRPV4 Q9HBA0 1/20 0.53
KMT2A Q03164 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
MAPT P10636 1/20 0.53
GAA P10253 1/20 0.53
MAPK1 P28482 1/20 0.53
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
LMNA P02545 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29482636 1.00 L3MBTL1 (0.64) L3MBTL1TP53ALDH1A1NPSR1TRPV4
SCHEMBL5559496 0.85 L3MBTL1 (0.49) L3MBTL1TP53ALDH1A1NPSR1TRPV4
SCHEMBL74997 0.85 TRPV4 (0.68) L3MBTL1TP53ALDH1A1TRPV4GAA
SCHEMBL29482639 0.85 TRPV4 (0.68) L3MBTL1TP53ALDH1A1TRPV4GAA
SCHEMBL15220366 0.83 ALPL (0.51) L3MBTL1TP53TRPV4KMT2ASMN1; SMN2
SCHEMBL5984215 0.83 KDM4E (0.52) L3MBTL1TRPV4KMT2ASMN1; SMN2GAA
SCHEMBL1611864 0.83 L3MBTL1 (0.46) L3MBTL1TP53ALDH1A1NPSR1TRPV4
SCHEMBL17392336 0.83 MEN1 (0.60) L3MBTL1ALDH1A1TRPV4KMT2ASMN1; SMN2
SCHEMBL29652438 0.83 MEN1 (0.60) L3MBTL1ALDH1A1TRPV4KMT2ASMN1; SMN2
SCHEMBL5960683 0.82 SMN1; SMN2 (0.67) L3MBTL1TP53ALDH1A1NPSR1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 625 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104678028-A Pretreatment and detection method for biogen amine neurotransmitter and detection kit INST PHARM & TOXICOLOGY AMMS 2015-06-03 CN claimed
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 EP claimed
US-12630529-B2 GCN2 modulator compounds Alesta Therapeutics BV (NL) 2026-05-19 US disclosed
US-20260062393-A1 Compounds CTXT PTY LTD (AU) 2026-03-05 US disclosed
US-12365655-B2 Compounds CTXT PTY LTD (AU) 2025-07-22 US disclosed
WO-2025100970-A1 TNAP INHIBITORY COMPOUND AND USE THEREOF 주식회사 레드엔비아 2025-05-15 WO disclosed
US-20250122182-A1 MYST Inhibitors Isosterix, Inc. 2025-04-17 US disclosed
WO-2025075722-A1 PRODUCTION METHOD FOR SOLID CATALYST COMPONENT FOR POLYMERIZING OLEFINS, AND CATALYST FOR POLYMERIZAING OLEFINS FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2025-04-10 WO disclosed
US-20250115687-A1 PRODUCTION METHOD FOR SOLID CATALYST COMPONENT FOR POLYMERIZING OLEFINS, AND CATALYST FOR POLYMERIZAING OLEFINS FORMOSA PLASTICS CORP USA (US) 2025-04-10 US disclosed
EP-4335439-A2 COMPOUNDS CTXT PTY LTD (AU) 2024-03-13 EP disclosed
US-11912668-B2 GCN2 and perk kinase inhibitors and methods of use thereof DECIPHERA PHARMACEUTICALS, LLC (US) 2024-02-27 US disclosed
WO-1994005639-A1 SULFONAMIDE INHIBITORS OF HIV-ASPARTYL PROTEASE VERTEX PHARMACEUTICALS INCORPORATED (US) 1994-03-17 WO disclosed
US-5272128-A Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1993-12-21 US disclosed
EP-0511826-A2 Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1992-11-04 EP disclosed
US-4806145-A Herbicidal aryl triazolinones FMC CORPORATION (US) 1989-02-21 US disclosed
US-4743291-A Herbicidal aryl triazolinones FMC CORPORATION (US) 1988-05-10 US disclosed
EP-0199794-A4 HERBICIDAL ARYL TRIAZOLINONES. FMC CORP (US) 1987-09-28 EP disclosed
EP-0199794-A1 HERBICIDAL ARYL TRIAZOLINONES FMC Corporation (US) 1986-11-05 EP disclosed
WO-1986002642-A1 HERBICIDAL ARYL TRIAZOLINONES FMC CORPORATION (US) 1986-05-09 WO disclosed
US-3988468-A 7-Methoxy-6-thiatetracyclines and their preparation MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1976-10-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630529-B2 GCN2 modulator compounds NR3C1, GCN1, EIF2AK4 L3MBTL1 1704/4885TP53 4741/4885ALDH1A1 4260/4885
US-20260062393-A1 Compounds SCN2B, ABCB11, SCN1B L3MBTL1 3817/4885TP53 4584/4885ALDH1A1 1864/4885
US-20250122182-A1 MYST Inhibitors MNAT1, SUGT1, ACAT2 L3MBTL1 1245/4885TP53 14/4885ALDH1A1 3906/4885
US-11912668-B2 GCN2 and perk kinase inhibitors and methods of use thereof EIF2AK4, GCN1, MAPKAPK2 L3MBTL1 2102/4885TP53 3755/4885ALDH1A1 4542/4885
US-12365655-B2 Compounds SLC10A1, ABCB11, PCSK9 L3MBTL1 4863/4885TP53 3504/4885ALDH1A1 982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.