Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7321462 | 0.86 | CYP4F2 (0.47) | PTPN1CYP4F2CYP4A11CYP1A2GAA | |
| SCHEMBL7327811 | 0.83 | TSHR (0.44) | PTPN1ALDH1A1LMNAHSD17B10MAPT | |
| SCHEMBL16267759 | 0.81 | ALOX15 (0.55) | PTPN1CYP4F2CYP4A11CYP1A2GAA | |
| SCHEMBL5731374 | 0.77 | CYP4F2 (0.47) | PTPN1CYP4F2CYP4A11GAAALDH1A1 | |
| SCHEMBL7322408 | 0.76 | NPSR1 (0.42) | PTPN1ALDH1A1ALOX15 | |
| SCHEMBL7325105 | 0.74 | MAPT (0.60) | PTPN1CYP4F2CYP4A11CYP1A2ALDH1A1 | |
| SCHEMBL8125088 | 0.72 | ALOX15 (0.41) | PTPN1ALDH1A1LMNAMAPTALOX15 | |
| SCHEMBL7329653 | 0.72 | TDP1 (0.66) | CYP4F2CYP4A11CYP1A2ALDH1A1LMNA | |
| SCHEMBL23640239 | 0.71 | MAPT (0.42) | PTPN1ALDH1A1LMNAMAPTALOX15 | |
| Succinic Acid Diethyl Ester SCHEMBL22780 | 0.70 | GAA (0.67) | CYP4F2CYP4A11CYP1A2GAAMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4525361-A | FOR PHYSIOLOGICAL HOST DEFENSE CONTROL ACTIVITY IN MAMMALS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-06-25 | — | — | US | disclosed |
| US-4407757-A | IMMUNOLOGY AGENT, MUSCLE RELAXANT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-10-04 | — | — | US | disclosed |
| US-4271083-A | IMMUNO-POTENTIATING ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-06-02 | — | — | US | disclosed |
| US-4139545-A | IMMUNO-POTENTIATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-02-13 | — | — | US | disclosed |