Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15695040 | 0.85 | MAPT (0.53) | MAPTTDP1ALDH1A1THRBALOX15 | |
| SCHEMBL14894797 | 0.83 | MAPT (0.61) | MAPTTDP1ALDH1A1THRBALOX15 | |
| Utreloxastat SCHEMBL1713853 | 0.81 | MAPT (0.65) | MAPTTDP1ALDH1A1THRBALOX15 | |
| SCHEMBL21854615 | 0.81 | MAPT (0.65) | MAPTTDP1ALDH1A1THRBALOX15 | |
| SCHEMBL12134627 | 0.81 | MAPT (0.65) | MAPTTDP1ALDH1A1THRBALOX15 | |
| SCHEMBL9578634 | 0.79 | MAPT (0.52) | MAPTTDP1ALDH1A1THRBALOX15 | |
| SCHEMBL10295726 | 0.78 | ALOX15 (0.35) | MAPTTDP1ALDH1A1THRBALOX15 | |
| SCHEMBL10446588 | 0.77 | MAPT (0.44) | MAPTTDP1ALDH1A1THRBALOX15 | |
| SCHEMBL22026825 | 0.77 | ALOX15 (0.40) | MAPTTDP1ALDH1A1THRBALOX15 | |
| SCHEMBL6576123 | 0.75 | MAPT (0.73) | MAPTTDP1ALDH1A1THRBIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12037350-B2 | Compositions and methods for the prevention and/or treatment of mitochondrial disease, including Friedreich's ataxia | STEALTH BIOTHERAPEUTICS INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-20210214607-A1 | LONG WAVELENGTH EMITTING CHEMILUMINESCENT PROBES | NEMIS TECHNOLOGIES AG (CH) | 2021-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12037350-B2 | Compositions and methods for the prevention and/or treatment of mitochondrial disease, including Friedreich's ataxia | FH, COQ8A, TFAM | MAPT 916/4885TDP1 181/4885ALDH1A1 646/4885 |
| US-20210214607-A1 | LONG WAVELENGTH EMITTING CHEMILUMINESCENT PROBES | VEGFA, GUSB, NR2E3 | MAPT 3254/4885TDP1 599/4885ALDH1A1 297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.