Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.88 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7331187 | 0.94 | PPARA (1.00) | PPARASMN1; SMN2NPSR1ALOX5 | |
| SCHEMBL11374053 | 0.93 | PPARA (0.80) | PPARASMN1; SMN2NPSR1ALOX5 | |
| SCHEMBL11359594 | 0.91 | PPARA (0.82) | PPARASMN1; SMN2NPSR1ALOX5 | |
| SCHEMBL7324319 | 0.89 | PPARA (0.70) | PPARASMN1; SMN2NPSR1ALOX5 | |
| SCHEMBL7324522 | 0.87 | PPARA (0.76) | PPARASMN1; SMN2 | |
| SCHEMBL11364057 | 0.85 | PPARA (0.79) | PPARASMN1; SMN2NPSR1ALOX5 | |
| SCHEMBL7325872 | 0.84 | PPARA (0.82) | PPARASMN1; SMN2NPSR1ALOX5 | |
| SCHEMBL7324266 | 0.84 | PPARA (0.82) | PPARASMN1; SMN2NPSR1 | |
| SCHEMBL11368265 | 0.84 | PPARA (0.82) | PPARA | |
| SCHEMBL2837046 | 0.82 | PPARA (0.79) | PPARAALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0067685-B1 | ALPHA-PHENYL-2-(AZA)BENZOTHIAZOLYLTHIOGLYCOLIC ACIDS AND DERIVATIVES THEREOF | AMERICAN HOME PRODUCTS CORPORATION (US) | 1986-11-05 | — | — | EP | claimed |
| US-4567267-A | α-Phenyl-2-(aza)benzothiazolylthioglycolic acids and derivatives thereof | AMERICAN HOME PRODUCTS CORPORATION (US) | 1986-01-28 | — | — | US | claimed |
| US-4367233-A | ALPHA-PHENYL-2-/AZA/BENZOTHIAZOYLTHIOGLYCOLIC ACIDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1983-01-04 | — | — | US | claimed |
| EP-0067685-A1 | Alpha-phenyl-2-(aza)benzothiazolylthioglycolic acids and derivatives thereof | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-12-22 | — | — | EP | claimed |
| EP-0067685-B1 | ALPHA-PHENYL-2-(AZA)BENZOTHIAZOLYLTHIOGLYCOLIC ACIDS AND DERIVATIVES THEREOF | AMERICAN HOME PRODUCTS CORPORATION (US) | 1986-11-05 | — | — | EP | disclosed |
| US-4567267-A | α-Phenyl-2-(aza)benzothiazolylthioglycolic acids and derivatives thereof | AMERICAN HOME PRODUCTS CORPORATION (US) | 1986-01-28 | — | — | US | disclosed |
| US-4367233-A | ALPHA-PHENYL-2-/AZA/BENZOTHIAZOYLTHIOGLYCOLIC ACIDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1983-01-04 | — | — | US | disclosed |
| EP-0067685-A1 | Alpha-phenyl-2-(aza)benzothiazolylthioglycolic acids and derivatives thereof | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-12-22 | — | — | EP | disclosed |