Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.82 |
| ▸ | ACP1 | P24666 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7331187 | 0.90 | PPARA (1.00) | PPARANPC1MAPT | |
| SCHEMBL11368015 | 0.86 | PPARA (0.65) | PPARANPC1MAPTDYRK1A | |
| SCHEMBL7324522 | 0.86 | PPARA (0.76) | PPARAMAPT | |
| SCHEMBL11397881 | 0.85 | PPARA (0.61) | PPARANPC1MAPT | |
| SCHEMBL7322651 | 0.84 | PPARA (0.72) | PPARANPC1MAPT | |
| SCHEMBL7325252 | 0.84 | PPARA (0.88) | PPARA | |
| SCHEMBL11366252 | 0.82 | PPARA (0.60) | PPARAACP1NPC1MAPT | |
| SCHEMBL7324620 | 0.81 | PDK1 (0.60) | PPARAACP1NPC1MAPTDYRK1A | |
| SCHEMBL11359594 | 0.81 | PPARA (0.82) | PPARA | |
| SCHEMBL7325872 | 0.81 | PPARA (0.82) | PPARANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4294839-A | Benzothiazole derivatives and pharmaceutical formulations containing them | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-10-13 | — | — | US | disclosed |
| EP-0030632-A2 | Benzothiazole derivatives, pharmaceutical compositions containing them and process for their preparation | MERCK PATENT GmbH (DE) | 1981-06-24 | — | — | EP | disclosed |