Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | BRS3 | P32247 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315999 | 0.95 | MEN1 (0.46) | MEN1KMT2AMTNR1BMTNR1AALDH1A1 | |
| SCHEMBL7324219 | 0.94 | MEN1 (0.42) | MEN1KMT2AMTNR1BMTNR1AALDH1A1 | |
| SCHEMBL7318337 | 0.91 | MEN1 (0.46) | MEN1KMT2AMTNR1BMTNR1AALDH1A1 | |
| SCHEMBL7322098 | 0.91 | MTNR1A (0.48) | MEN1KMT2AMTNR1BMTNR1AGAA | |
| SCHEMBL7317804 | 0.90 | KMT2A (0.54) | MEN1KMT2AMTNR1BMTNR1AALDH1A1 | |
| SCHEMBL7312999 | 0.90 | MEN1 (0.45) | MEN1KMT2AMTNR1BMTNR1AALDH1A1 | |
| SCHEMBL7314673 | 0.90 | MEN1 (0.48) | MEN1KMT2AMTNR1BMTNR1AALDH1A1 | |
| SCHEMBL7321200 | 0.88 | MEN1 (0.44) | MEN1KMT2AMTNR1BMTNR1AALDH1A1 | |
| SCHEMBL7318735 | 0.87 | KMT2A (0.46) | MEN1KMT2AMTNR1BMTNR1AALDH1A1 | |
| SCHEMBL7315552 | 0.86 | MEN1 (0.48) | MEN1KMT2AMTNR1BMTNR1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929097-A | INHIBIT TUMOR NECROSIS FACTOR-ALPHA CONVERTING ENZYME | AMERICAN CYANAMID COMPANY (US) | 1999-07-27 | — | — | US | disclosed |