Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7317547 | 0.94 | MEN1 (0.42) | MEN1KMT2AMCL1ALDH1A1MTNR1A | |
| SCHEMBL7317804 | 0.91 | KMT2A (0.54) | MEN1KMT2AMCL1ALDH1A1BCL2L1 | |
| SCHEMBL7322098 | 0.88 | MTNR1A (0.48) | MEN1KMT2AMTNR1AMTNR1BGAA | |
| SCHEMBL7314673 | 0.87 | MEN1 (0.48) | MEN1KMT2AMCL1ALDH1A1BCL2L1 | |
| SCHEMBL7313454 | 0.86 | ACLY (0.51) | MEN1KMT2AMCL1ALDH1A1BCL2L1 | |
| SCHEMBL7325264 | 0.86 | MEN1 (0.47) | MEN1KMT2AMCL1ALDH1A1BCL2L1 | |
| SCHEMBL7315999 | 0.85 | MEN1 (0.46) | MEN1KMT2AMCL1ALDH1A1BCL2L1 | |
| SCHEMBL7318337 | 0.84 | MEN1 (0.46) | MEN1KMT2AALDH1A1MTNR1AMTNR1B | |
| SCHEMBL7318735 | 0.84 | KMT2A (0.46) | MEN1KMT2AMCL1ALDH1A1BCL2L1 | |
| SCHEMBL7351226 | 0.84 | MEN1 (0.48) | MEN1KMT2AMCL1ALDH1A1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929097-A | INHIBIT TUMOR NECROSIS FACTOR-ALPHA CONVERTING ENZYME | AMERICAN CYANAMID COMPANY (US) | 1999-07-27 | — | — | US | disclosed |