SCHEMBL7325355

SCHEMBL7325355

CCN(CC#Cc1ccc(C2CCCCC2)c(Cl)c1)C1CCCCC1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.56
TMEM97 Q5BJF2 1/20 0.56
EBP Q15125 1/20 0.56
TSHR P16473 2/20 0.34
CYP2D6 P10635 2/20 0.34
CYP2C9 P11712 1/20 0.34
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31
KCNH2 Q12809 1/20 0.31
CYP11B2 P19099 1/20 0.31
SLC6A4 P31645 1/20 0.30
CEL P19835 1/20 0.30
NOS3 P29474 1/20 0.30
NOS1 P29475 1/20 0.30
NOS2 P35228 1/20 0.30
FASN P49327 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29412738 1.00 SIGMAR1 (0.56) SIGMAR1TMEM97EBPTSHRCYP2D6
Hydrochloric Acid SCHEMBL9148670 0.99 SIGMAR1 (0.55) SIGMAR1TMEM97EBPTSHRCYP2D6
SCHEMBL26765552 0.85 SIGMAR1 (0.44) SIGMAR1TMEM97EBPSLC6A4NOS3
SCHEMBL26765546 0.85 SIGMAR1 (0.43) SIGMAR1TMEM97EBPTSHRCYP2D6
SCHEMBL7135842 0.85 SIGMAR1 (0.41) SIGMAR1TMEM97EBPTSHRCYP2D6
SCHEMBL7144481 0.84 SIGMAR1 (0.38) SIGMAR1TMEM97EBPTSHRCYP2D6
Hydrochloric Acid SCHEMBL9151770 0.84 SIGMAR1 (0.43) SIGMAR1TMEM97EBPSLC6A4NOS3
SCHEMBL8329033 0.84 SIGMAR1 (0.42) SIGMAR1TMEM97EBPTSHRCYP2D6
Hydrochloric Acid SCHEMBL9319142 0.84 SIGMAR1 (0.42) SIGMAR1TMEM97EBPTSHRCYP2D6
Hydrochloric Acid SCHEMBL7310901 0.83 SIGMAR1 (0.41) SIGMAR1TMEM97EBPTSHRCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0917464-A1 USE OF AMINES TO PRODUCE DRUGS FOR PREVENTING TUMOUR CELL PROLIFERATION SANOFI (FR) 1999-05-26 EP claimed
WO-1998004251-A1 USE OF AMINES TO PRODUCE DRUGS FOR PREVENTING TUMOUR CELL PROLIFERATION SANOFI (FR) 1998-02-05 WO claimed
US-20260062374-A1 PROCESS FOR THE PREPARATION OF A BENZENE DERIVATIVE MELETIOS THERAPEUTICS (FR) 2026-03-05 US disclosed
WO-2024042246-A1 PROCESS FOR THE PREPARATION OF A BENZENE DERIVATIVE MELETIOS THERAPEUTICS (FR) 2024-02-29 WO disclosed
WO-2024042246-A1 PROCESS FOR THE PREPARATION OF A BENZENE DERIVATIVE MELETIOS THERAPEUTICS (FR) 2024-02-29 WO disclosed
US-20230364033-A1 COMPOUNDS FOR TREATING VIRUS INFECTIONS MELETIOS THERAPEUTICS (FR) 2023-11-16 US disclosed
US-20230364033-A1 COMPOUNDS FOR TREATING VIRUS INFECTIONS MELETIOS THERAPEUTICS (FR) 2023-11-16 US disclosed
US-20230364033-A1 COMPOUNDS FOR TREATING VIRUS INFECTIONS MELETIOS THERAPEUTICS (FR) 2023-11-16 US disclosed
CN-1154483-C Use of amines to produce drugs for preventing tumour cell proliferation ��ŵ��-ʥ�������ɷ����޹�˾ 2004-06-23 CN disclosed
US-6235791-B1 USING CIS N-CYCLOHEXYL-N-ETHYL(3-(3-CHLORO-CYCLOHEXYLPHENYL)ALLYL)AMINE SANOFI-SYNTHELABO (FR) 2001-05-22 US disclosed
CN-1226825-A Use of amines to produce drugs for preventing tumour cell proliferation SANOFI SA (FR) 1999-08-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062374-A1 PROCESS FOR THE PREPARATION OF A BENZENE DERIVATIVE BRDT, CYP3A7, TP53 SIGMAR1 39/4885TMEM97 7/4885EBP 249/4885
US-20230364033-A1 COMPOUNDS FOR TREATING VIRUS INFECTIONS ACE, HAVCR2, FURIN SIGMAR1 3429/4885TMEM97 3055/4885EBP 660/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.