Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7240119 | 0.86 | ALDH1A1 (0.50) | LMNAALDH1A1HSD17B10KDM4EKMT2A | |
| SCHEMBL6029302 | 0.84 | ALDH1A1 (0.48) | LMNAALDH1A1HSD17B10USP2KDM4E | |
| SCHEMBL8182332 | 0.81 | ALDH1A1 (0.44) | LMNAALDH1A1HSD17B10USP2KDM4E | |
| SCHEMBL13996208 | 0.77 | TDP1 (0.45) | LMNAALDH1A1HSD17B10KDM4EKMT2A | |
| SCHEMBL32691108 | 0.76 | ALDH1A1 (0.53) | LMNAALDH1A1HSD17B10KDM4EKMT2A | |
| SCHEMBL29459236 | 0.76 | ALDH1A1 (0.53) | LMNAALDH1A1HSD17B10KDM4EKMT2A | |
| SCHEMBL6243248 | 0.76 | ALDH1A1 (0.53) | LMNAALDH1A1HSD17B10KDM4EKMT2A | |
| SCHEMBL19359521 | 0.73 | TP53 (0.49) | LMNAALDH1A1HSD17B10KDM4EKMT2A | |
| SCHEMBL29287064 | 0.73 | TP53 (0.49) | LMNAALDH1A1HSD17B10KDM4EKMT2A | |
| SCHEMBL19370668 | 0.73 | TP53 (0.49) | LMNAALDH1A1HSD17B10KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328700-A1 | 4,7-Dihydropyrazolo(1,5-a)pyrimidine compound and pharmaceutical use thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-08-23 | — | — | EP | disclosed |