Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29459236 | 1.00 | ALDH1A1 (0.53) | ALDH1A1GAAPOLBKDM4ETP53 | |
| SCHEMBL32691108 | 1.00 | ALDH1A1 (0.53) | ALDH1A1GAAPOLBKDM4ETP53 | |
| SCHEMBL32691229 | 0.84 | ALDH1A1 (0.68) | ALDH1A1GAAPOLBKDM4ETP53 | |
| SCHEMBL3716759 | 0.84 | ALDH1A1 (0.54) | ALDH1A1GAAPOLBKDM4ETP53 | |
| SCHEMBL20835844 | 0.84 | ALDH1A1 (0.68) | ALDH1A1GAAPOLBKDM4ETP53 | |
| SCHEMBL10201311 | 0.84 | ALDH1A1 (0.68) | ALDH1A1GAAPOLBKDM4ETP53 | |
| SCHEMBL512864 | 0.84 | ALDH1A1 (0.68) | ALDH1A1GAAPOLBKDM4ETP53 | |
| SCHEMBL6285244 | 0.84 | ALDH1A1 (0.50) | ALDH1A1GAAPOLBKDM4ETP53 | |
| SCHEMBL12291598 | 0.83 | ALDH1A1 (0.60) | ALDH1A1GAAPOLBKDM4ETP53 | |
| SCHEMBL5422287 | 0.83 | ALDH1A1 (0.60) | ALDH1A1GAAPOLBKDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113614074-A | Amino acid derivatives for the treatment of inflammatory diseases | 罗斯坎普研究所 | 2021-11-05 | — | — | CN | disclosed |
| EP-1549323-A2 | CONJUGATES COMPRISING CENTRAL NERVOUS SYSTEM ACTIVE DRUG | A & D Bioscience, Inc. (US) | 2005-07-06 | — | — | EP | disclosed |
| WO-2003094842-A2 | CONJUGATES COMPRISING CENTRAL NERVOUS SYSTEM ACTIVE DRUG | A & D BIOSCIENCE, INC. (US) | 2003-11-20 | — | — | WO | disclosed |
| US-5270338-A | Acetazolamide-related compounds, process for their preparation, and pharmaceutical composition containing the same | ISTITUTO CHIMICO INTERNAZIONALE DR. GIUSEPPE RENDE S.R.L. (IT) | 1993-12-14 | — | — | US | disclosed |
| EP-0354881-B1 | ACETAZOLAMIDE-RELATED COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | ISTITUTO CHIMICO INTERNAZIONALE DR. GIUSEPPE RENDE S.R.L. (IT) | 1992-04-22 | — | — | EP | disclosed |
| US-5010204-A | Glaucoma treatment | INSTITUTO CHIMICO INTERNAZIONALE DR. GIUSEPPE RENDE S.R.L. (IT) | 1991-04-23 | — | — | US | disclosed |
| EP-0354881-A1 | Acetazolamide-related compounds, process for their preparation, and pharmaceutical composition containing the same | ISTITUTO CHIMICO INTERNAZIONALE DR. GIUSEPPE RENDE S.R.L. (IT) | 1990-02-14 | — | — | EP | disclosed |