Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 20/20 | 0.59 |
| ▸ | MMP13 | P45452 | 15/20 | 0.58 |
| ▸ | MMP1 | P03956 | 10/20 | 0.58 |
| ▸ | MMP2 | P08253 | 8/20 | 0.53 |
| ▸ | MMP14 | P50281 | 6/20 | 0.53 |
| ▸ | MMP9 | P14780 | 5/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6786688 | 0.85 | ADAM17 (0.62) | ADAM17MMP13MMP1MMP2MMP14 | |
| SCHEMBL6658136 | 0.82 | ADAM17 (0.68) | ADAM17MMP13MMP1MMP2MMP14 | |
| SCHEMBL6786664 | 0.77 | ADAM17 (0.83) | ADAM17MMP13MMP1MMP2MMP14 | |
| SCHEMBL6626726 | 0.76 | ADAM17 (0.84) | ADAM17MMP13MMP1MMP2MMP14 | |
| SCHEMBL7325091 | 0.76 | ADAM17 (0.61) | ADAM17MMP13MMP1MMP2MMP14 | |
| SCHEMBL6654489 | 0.74 | ADAM17 (1.00) | ADAM17MMP13MMP1MMP2MMP14 | |
| SCHEMBL6508043 | 0.74 | ADAM17 (0.76) | ADAM17MMP13MMP1MMP2MMP14 | |
| SCHEMBL7365665 | 0.74 | ADAM17 (0.82) | ADAM17MMP13MMP1MMP2MMP14 | |
| SCHEMBL6264635 | 0.74 | ADAM17 (0.82) | ADAM17MMP13MMP1MMP2MMP14 | |
| SCHEMBL3939658 | 0.74 | ADAM17 (1.00) | ADAM17MMP13MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340691-B1 | TREATMENT OF ARTHRITIS, TUMOR METASTASIS, TISSUE ULCERATION, ABNORMAL WOUND HEALING, PERIODONTAL DISEASE, BONE DISEASE, DIABETES (INSULIN RESISTANCE) AND HIV INFECTION | AMERICAN CYANAMID COMPANY | 2002-01-22 | — | — | US | claimed |