Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15434608 | 0.80 | SMN1; SMN2 (0.56) | GLASMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL28005538 | 0.78 | GLA (0.69) | GLASMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL7361325 | 0.75 | HSD17B10 (0.48) | GLASMN1; SMN2KMT2AALDH1A1MEN1 | |
| SCHEMBL14002787 | 0.75 | GLA (0.60) | GLASMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL7366975 | 0.74 | KDM4E (0.48) | GLASMN1; SMN2KMT2AALDH1A1MEN1 | |
| SCHEMBL23747134 | 0.74 | GLA (0.58) | GLASMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL12428914 | 0.74 | SMN1; SMN2 (0.62) | GLASMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL26383496 | 0.73 | SMN1; SMN2 (0.57) | GLASMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL545027 | 0.73 | GLA (0.96) | GLASMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL28884585 | 0.71 | ARG1 (0.55) | GLASMN1; SMN2KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614522-A | SULFONAMIDE AND UREA-CONTAINING HYDROXYETHYLAMINE COMPOUNDS | G.D. SEARLE & CO. (US) | 1997-03-25 | — | — | US | disclosed |
| EP-0558673-B1 | RETROVIRAL PROTEASE INHIBITORS | MONSANTO CO (US) | 1996-04-17 | — | — | EP | disclosed |
| EP-0558673-A1 | RETROVIRAL PROTEASE INHIBITORS. | MONSANTO CO (US) | 1993-09-08 | — | — | EP | disclosed |
| WO-1992008699-A1 | RETROVIRAL PROTEASE INHIBITORS | MONSANTO COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |