SCHEMBL15434608

SCHEMBL15434608

CC(C)(CCN1CCOCC1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.56
KMT2A Q03164 4/20 0.53
MEN1 O00255 2/20 0.53
GLA P06280 1/20 0.52
OPRM1 P35372 1/20 0.50
OPRD1 P41143 1/20 0.50
ARG1 P05089 1/20 0.49
ARG2 P78540 1/20 0.49
HSD17B10 Q99714 1/20 0.46
LMNA P02545 3/20 0.43
ALDH1A1 P00352 4/20 0.43
KDM4E B2RXH2 2/20 0.43
CYP2C19 P33261 1/20 0.43
MAPT P10636 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8843134 0.85 SMN1; SMN2 (0.56) SMN1; SMN2KMT2AMEN1GLAOPRM1
SCHEMBL15434606 0.84 SMN1; SMN2 (0.54) SMN1; SMN2KMT2AMEN1GLAOPRM1
SCHEMBL28884585 0.84 ARG1 (0.55) SMN1; SMN2KMT2AMEN1GLAOPRM1
SCHEMBL27911982 0.82 ARG1 (0.45) SMN1; SMN2OPRM1ARG1ARG2LMNA
SCHEMBL7327831 0.81 PAOX (0.43) SMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL7361325 0.81 HSD17B10 (0.48) SMN1; SMN2KMT2AMEN1GLAOPRM1
SCHEMBL7325836 0.80 GLA (0.54) SMN1; SMN2KMT2AMEN1GLAOPRM1
SCHEMBL7366975 0.80 KDM4E (0.48) SMN1; SMN2KMT2AMEN1GLAALDH1A1
Hydrochloric Acid SCHEMBL11725592 0.79 ARG1 (0.46) SMN1; SMN2KMT2AMEN1OPRM1ARG1
SCHEMBL12463688 0.78 SMN1; SMN2 (0.49) SMN1; SMN2KMT2AMEN1GLAOPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240229026-A1 CHIRAL CONTROL WAVE LIFE SCIENCES LTD. (SG) 2024-07-11 US disclosed
US-20240229026-A1 CHIRAL CONTROL WAVE LIFE SCIENCES LTD. (SG) 2024-07-11 US disclosed
EP-4219516-A2 CHIRAL CONTROL Wave Life Sciences Ltd. (SG) 2023-08-02 EP disclosed
US-11643657-B2 Chiral control WAVE LIFE SCIENCES LTD. (SG) 2023-05-09 US disclosed
US-11643657-B2 Chiral control WAVE LIFE SCIENCES LTD. (SG) 2023-05-09 US disclosed
EP-2872147-B1 METHOD FOR MAKING CHIRAL OLIGONUCLEOTIDES WAVE LIFE SCIENCES LTD (SG) 2022-12-21 EP disclosed
US-20210130821-A1 CHIRAL CONTROL WAVE LIFE SCIENCES LTD. (SG) 2021-05-06 US disclosed
US-10590413-B2 Chiral control WAVE LIFE SCIENCES LTD. (SG) 2020-03-17 US disclosed
US-9982257-B2 Chiral control WAVE LIFE SCIENCES LTD. (SG) 2018-05-29 US disclosed
US-9885037-B2 2018-02-06 US disclosed
US-20170275621-A1 CHIRAL CONTROL WAVE LIFE SCIENCES USA, INC. 2017-09-28 US disclosed
US-20170275621-A1 CHIRAL CONTROL WAVE LIFE SCIENCES USA, INC. 2017-09-28 US disclosed
US-20150211006-A1 CHIRAL CONTROL WAVE LIFE SCIENCES USA, INC. 2015-07-30 US disclosed
US-20150211006-A1 CHIRAL CONTROL WAVE LIFE SCIENCES USA, INC. 2015-07-30 US disclosed
WO-2014012081-A2 CHIRAL CONTROL ONTORII, INC. (US) 2014-01-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210130821-A1 CHIRAL CONTROL RNGTT, POLI, NSUN3 SMN1; SMN2 695/4885KMT2A 2211/4885MEN1 2026/4885
US-20170275621-A1 CHIRAL CONTROL RNGTT, POLI, NSUN3 SMN1; SMN2 695/4885KMT2A 2211/4885MEN1 2026/4885
US-20240229026-A1 CHIRAL CONTROL RNGTT, POLI, NSUN3 SMN1; SMN2 695/4885KMT2A 2211/4885MEN1 2026/4885
US-20150211006-A1 CHIRAL CONTROL RNGTT, POLI, NSUN3 SMN1; SMN2 695/4885KMT2A 2211/4885MEN1 2026/4885
US-11643657-B2 Chiral control RNGTT, POLI, NSUN3 SMN1; SMN2 695/4885KMT2A 2211/4885MEN1 2026/4885
US-10590413-B2 Chiral control RNGTT, POLI, NSUN3 SMN1; SMN2 695/4885KMT2A 2211/4885MEN1 2026/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.