Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 16/20 | 0.76 |
| ▸ | CTSL | P07711 | 15/20 | 0.76 |
| ▸ | CTSS | P25774 | 11/20 | 0.76 |
| ▸ | CTSB | P07858 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7325885 | 1.00 | CTSK (0.76) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7322234 | 0.91 | CTSK (0.75) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7441730 | 0.86 | CTSK (1.00) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7443679 | 0.86 | CTSK (1.00) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7325867 | 0.85 | CTSK (0.76) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7312534 | 0.83 | CTSK (0.64) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7320892 | 0.83 | CTSK (0.64) | CTSKCTSLCTSSCTSB | |
| SCHEMBL8086278 | 0.82 | CTSK (0.88) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7450469 | 0.82 | CTSK (0.88) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7444598 | 0.79 | CTSK (1.00) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232305-B1 | ANTICANCER AGENTS; BONE DISORDERS; ANTIARTHRITIC AGENTS; RESPIRATORY SYSTEM DISORDERS | NAEJA PHARMACEUTICAL INC. (CA) | 2001-05-15 | — | — | US | disclosed |
| EP-0961779-A1 | SUBSTITUTED AMINO BICYCLIC-$g(b)-LACTAM PENAM AND CEPHAM DERIVATIVES AS CYSTEINE PROTEASE INHIBITORS | SYNPHAR LABORATORIES INC. (CA) | 1999-12-08 | — | — | EP | disclosed |
| WO-1998032766-A1 | SUBSTITUTED AMINO BICYCLIC-β-LACTAM PENAM AND CEPHAM DERIVATIVES AS CYSTEINE PROTEASE INHIBITORS | SYNPHAR LABORATORIES INC. (US) | 1998-07-30 | — | — | WO | disclosed |