Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 17/20 | 1.00 |
| ▸ | CTSL | P07711 | 14/20 | 1.00 |
| ▸ | CTSS | P25774 | 12/20 | 1.00 |
| ▸ | CTSB | P07858 | 4/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7441730 | 1.00 | CTSK (1.00) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7450469 | 0.93 | CTSK (0.88) | CTSKCTSLCTSSCTSB | |
| SCHEMBL8086278 | 0.93 | CTSK (0.88) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7325885 | 0.86 | CTSK (0.76) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7325878 | 0.86 | CTSK (0.76) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7325867 | 0.86 | CTSK (0.76) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7322234 | 0.85 | CTSK (0.75) | CTSKCTSLCTSSCTSB | |
| SCHEMBL8356963 | 0.84 | CTSK (0.72) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7449383 | 0.82 | CTSK (1.00) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7503835 | 0.81 | CTSK (0.68) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0817795-B1 | NOVEL 4-SUBSTITUTED-3-PEPTIDYL-AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE INHIBITOR | NAEJA PHARMACEUTICAL INC (CA) | 2000-11-15 | — | — | EP | claimed |
| US-5986108-A | ENZYME INHIBITORS | SYNPHAR LABORATORIES, INC. (CA) | 1999-11-16 | — | — | US | claimed |
| EP-0817795-B1 | NOVEL 4-SUBSTITUTED-3-PEPTIDYL-AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE INHIBITOR | NAEJA PHARMACEUTICAL INC (CA) | 2000-11-15 | — | — | EP | disclosed |
| US-5986108-A | ENZYME INHIBITORS | SYNPHAR LABORATORIES, INC. (CA) | 1999-11-16 | — | — | US | disclosed |
| EP-0817795-A1 | NOVEL 4-SUBSTITUTED-3-PEPTIDYL-AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE INHIBITOR | SYNPHAR LABORATORIES INC. (CA) | 1998-01-14 | — | — | EP | disclosed |
| WO-1996032408-A1 | NOVEL 4-SUBSTITUTED-3-PEPTIDYL-AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE INHIBITOR | SYNPHAR LABORATORIES, INC. (US) | 1996-10-17 | — | — | WO | disclosed |