Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 13/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7325827 | 0.99 | PDE4A (0.53) | PDE4APDE4BPDE4DPDE4CACHE | |
| Acetic Acid SCHEMBL2459347 | 0.93 | PDE4A (0.52) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL8574011 | 0.87 | PDE4A (0.52) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL29061973 | 0.85 | PDE4A (0.56) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL29061976 | 0.85 | PDE4A (0.56) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7322576 | 0.85 | PDE4A (0.55) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL11428703 | 0.84 | PDE4A (0.54) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL4637252 | 0.83 | PDE4A (0.60) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7352136 | 0.83 | PDE4A (0.54) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL8574005 | 0.83 | PDE4A (0.54) | PDE4APDE4BPDE4DPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557408-A4 | IMIDAZOLIDINONE COMPOUNDS | — | 1993-10-27 | — | — | EP | disclosed |
| EP-0557408-A1 | IMIDAZOLIDINONE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-09-01 | — | — | EP | disclosed |
| WO-1992007567-A1 | IMIDAZOLIDINONE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-05-14 | — | — | WO | disclosed |