Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4267683 | 0.84 | HRH3 (0.38) | SLC6A4SLC6A3HRH3MEN1KMT2A | |
| SCHEMBL4275497 | 0.82 | HRH3 (0.37) | HRH3MEN1KMT2AALDH1A1 | |
| SCHEMBL29106969 | 0.82 | HRH3 (0.37) | HRH3MEN1KMT2AALDH1A1 | |
| SCHEMBL4268661 | 0.82 | HRH3 (0.37) | HRH3MEN1KMT2AALDH1A1 | |
| SCHEMBL4281234 | 0.82 | HRH3 (0.37) | HRH3MEN1KMT2AALDH1A1 | |
| SCHEMBL2230356 | 0.82 | HRH3 (0.36) | SLC6A4SLC6A3HRH3DNM1MEN1 | |
| SCHEMBL12698815 | 0.82 | HRH3 (0.42) | SLC6A4SLC6A3HRH3DNM1MEN1 | |
| SCHEMBL4275008 | 0.80 | FDPS (0.36) | HRH3DNM1TSHR | |
| SCHEMBL4639527 | 0.80 | LMNA (0.36) | SLC6A4SLC6A3MEN1KMT2AALDH1A1 | |
| SCHEMBL4276675 | 0.80 | FDPS (0.36) | HRH3DNM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287696-B1 | ISOQUINOLINE DERIVATIVES | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1991-01-02 | — | — | EP | disclosed |
| EP-0287696-A1 | Isoquinoline derivatives | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1988-10-26 | — | — | EP | disclosed |