Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 14/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.56 |
| ▸ | PDE4A | P27815 | 4/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.51 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7327071 | 1.00 | PDE4B (0.59) | PDE4BPDE4DPDE4APDE4CPDE3A | |
| SCHEMBL7326510 | 0.95 | PDE4B (0.61) | PDE4BPDE4DPDE4APDE4CPDE3A | |
| SCHEMBL7326505 | 0.95 | PDE4B (0.61) | PDE4BPDE4DPDE4APDE4CPDE3A | |
| SCHEMBL7324806 | 0.85 | PDE4B (0.60) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7324802 | 0.85 | PDE4B (0.60) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7328448 | 0.84 | PDE4B (0.59) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7326305 | 0.84 | PDE4B (0.59) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL9577630 | 0.84 | PDE4B (0.59) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL70835 | 0.83 | ALDH1A1 (0.64) | PDE4BPDE4DPDE4APDE4CPDE3A | |
| SCHEMBL29808190 | 0.83 | ALDH1A1 (0.64) | PDE4BPDE4DPDE4APDE4CPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5274002-A | 1-Oxy- or -thio-2-cycloalkyloxy-4-carboxyalkylene benzene derivatives | WARNER-LAMBERT COMPANY (US) | 1993-12-28 | — | — | US | claimed |
| US-5274002-A | 1-Oxy- or -thio-2-cycloalkyloxy-4-carboxyalkylene benzene derivatives | WARNER-LAMBERT COMPANY (US) | 1993-12-28 | — | — | US | disclosed |
| US-4971959-A | Trisubstituted phenyl analogs having activity for congestive heart failure | WARNER-LAMBERT COMPANY (US) | 1990-11-20 | — | — | US | disclosed |