Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.60 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | PGA5 | P0DJD9 | 1/20 | 0.43 |
| ▸ | CTSE | P14091 | 1/20 | 0.43 |
| ▸ | PGC | P20142 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335979 | 0.93 | REN (0.53) | REN | |
| SCHEMBL7334448 | 0.92 | REN (0.60) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL9523190 | 0.91 | REN (0.56) | REN | |
| SCHEMBL7326156 | 0.90 | REN (0.54) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL7328163 | 0.90 | REN (0.59) | REN | |
| SCHEMBL7336297 | 0.88 | REN (0.54) | REN | |
| SCHEMBL7329901 | 0.87 | REN (0.56) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL7331214 | 0.87 | REN (0.58) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL7335814 | 0.87 | REN (0.71) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL7363064 | 0.87 | REN (0.59) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396065-A1 | Novel amino acid derivatives possessing renin-inhibitory activities | Japan Tobacco Inc. (JP) | 1990-11-07 | — | — | EP | claimed |
| EP-0396065-A1 | Novel amino acid derivatives possessing renin-inhibitory activities | Japan Tobacco Inc. (JP) | 1990-11-07 | — | — | EP | disclosed |