SCHEMBL7363064

SCHEMBL7363064

CC(C)C(O)CC(O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1c[nH]cn1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)CCc1cccnc1

nearest known ligand 0.59

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7326151 0.87 REN (0.60) REN
SCHEMBL7331214 0.85 REN (0.58) REN
SCHEMBL7334448 0.85 REN (0.60) REN
SCHEMBL7328163 0.85 REN (0.59) REN
SCHEMBL7335814 0.85 REN (0.71) REN
SCHEMBL9555326 0.85 REN (0.51) REN
SCHEMBL7329901 0.84 REN (0.56) REN
SCHEMBL7326379 0.84 REN (0.69) REN
SCHEMBL7326315 0.84 REN (0.78) REN
SCHEMBL7336297 0.84 REN (0.54) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0396065-A1 Novel amino acid derivatives possessing renin-inhibitory activities Japan Tobacco Inc. (JP) 1990-11-07 EP claimed
EP-0396065-A1 Novel amino acid derivatives possessing renin-inhibitory activities Japan Tobacco Inc. (JP) 1990-11-07 EP disclosed