Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.62 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29890737 | 0.83 | IDO1 (0.62) | IDO1GPR84ALDH1A1XBP1HTT | |
| SCHEMBL10340150 | 0.83 | IDO1 (0.62) | IDO1GPR84ALDH1A1XBP1HTT | |
| SCHEMBL20433788 | 0.83 | IDO1 (0.62) | IDO1GPR84ALDH1A1XBP1HTT | |
| SCHEMBL6689946 | 0.83 | IDO1 (0.67) | IDO1GPR84ALDH1A1SLC6A4MEN1 | |
| SCHEMBL8082622 | 0.83 | IDO1 (0.62) | IDO1GPR84ALDH1A1SLC6A4MEN1 | |
| SCHEMBL8334133 | 0.81 | IDO1 (0.60) | IDO1GPR84ALDH1A1XBP1HTT | |
| SCHEMBL4339523 | 0.80 | IDO1 (0.58) | IDO1GPR84ALDH1A1MEN1GAA | |
| SCHEMBL20433856 | 0.80 | GPR84 (0.59) | IDO1GPR84ALDH1A1HTTFFAR1 | |
| SCHEMBL19529546 | 0.80 | GPR84 (0.59) | IDO1GPR84ALDH1A1HTTFFAR1 | |
| SCHEMBL15330041 | 0.80 | IDO1 (0.72) | IDO1GPR84HTTSLC6A4GID4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4920227-A | Benzobicyclic carboxamide 5-HT3 antagonists | RORER PHARMACEUTICAL CORP. (US) | 1990-04-24 | — | — | US | disclosed |