Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.58 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257971 | 0.88 | IDO1 (0.53) | IDO1GPR84BRD4ATMALDH1A1 | |
| SCHEMBL12260702 | 0.84 | IDO1 (0.49) | IDO1GPR84BRD4ATMALDH1A1 | |
| SCHEMBL15818871 | 0.84 | GPR84 (0.70) | IDO1GPR84ALDH1A1MEN1GAA | |
| SCHEMBL19540929 | 0.82 | GPR84 (0.60) | IDO1GPR84TMEM97 | |
| SCHEMBL8082622 | 0.80 | IDO1 (0.62) | IDO1GPR84ALDH1A1MEN1GAA | |
| SCHEMBL7326172 | 0.80 | IDO1 (0.62) | IDO1GPR84ALDH1A1MEN1GAA | |
| SCHEMBL10340150 | 0.80 | IDO1 (0.62) | IDO1GPR84ALDH1A1KMT2AFFAR1 | |
| SCHEMBL29890737 | 0.80 | IDO1 (0.62) | IDO1GPR84ALDH1A1KMT2AFFAR1 | |
| SCHEMBL6689946 | 0.80 | IDO1 (0.67) | IDO1GPR84ALDH1A1MEN1GAA | |
| SCHEMBL20433788 | 0.80 | IDO1 (0.62) | IDO1GPR84ALDH1A1KMT2AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090036659-A1 | METHOD OF DEUTERATING BENZYL-POSITION IN -O-BENZYL GROUP | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| US-20090036659-A1 | METHOD OF DEUTERATING BENZYL-POSITION IN -O-BENZYL GROUP | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| US-20090036659-A1 | METHOD OF DEUTERATING BENZYL-POSITION IN -O-BENZYL GROUP | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1992605-A1 | METHOD OF DEUTERIZING BENZYL-POSITION IN -O-BENZYL GROUP | Wako Pure Chemical Industries, Ltd. (JP) | 2008-11-19 | — | — | EP | disclosed |
| EP-1992605-A1 | METHOD OF DEUTERIZING BENZYL-POSITION IN -O-BENZYL GROUP | Wako Pure Chemical Industries, Ltd. (JP) | 2008-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036659-A1 | METHOD OF DEUTERATING BENZYL-POSITION IN -O-BENZYL GROUP | DBH, BRD4, BRD3 | IDO1 750/4885GPR84 3805/4885BRD4 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.