Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16673142 | 0.87 | SMN1; SMN2 (0.48) | KMT2AHPGDALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL8089064 | 0.85 | FAAH (0.51) | FAAH | |
| SCHEMBL6190476 | 0.85 | KMT2A (0.48) | KMT2AHPGDALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL16156176 | 0.85 | KMT2A (0.48) | KMT2AHPGDALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL16149006 | 0.85 | KMT2A (0.48) | KMT2AHPGDALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL30423678 | 0.84 | FAAH (0.52) | KMT2AHPGDALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL8077436 | 0.84 | FAAH (0.47) | FAAH | |
| SCHEMBL28742911 | 0.84 | KMT2A (0.47) | KMT2AHPGDALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL7319532 | 0.83 | MAPT (0.51) | KMT2AHPGDALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL8251691 | 0.82 | SMN1; SMN2 (0.51) | KMT2ACYP2D6CYP2C9CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262431-A | Treating amnesia | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0275482-B1 | PROLINE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-01-20 | — | — | EP | disclosed |
| US-5112847-A | PROLINAL DERIVATIVES HAVING INHIBITORY ACTIVITY ON PROLYL ENDOPEPTIDASE | ONO PHARMACEUTICAL CO., LTD. (JP) | 1992-05-12 | — | — | US | disclosed |
| US-4983624-A | Anemia | ONO PHARMACEUTICAL CO., LTD (JP) | 1991-01-08 | — | — | US | disclosed |
| EP-0275482-A2 | Proline derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-07-27 | — | — | EP | disclosed |