Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084566 | 0.94 | KMT2A (0.43) | — | |
| SCHEMBL8084641 | 0.89 | GRIK1 (0.44) | — | |
| SCHEMBL8089064 | 0.84 | FAAH (0.51) | FAAHTRPA1MAPTRXFP1HDAC1 | |
| SCHEMBL8084679 | 0.84 | TRPA1 (0.48) | FAAHTRPA1MAPTRXFP1ALOX5 | |
| SCHEMBL7326178 | 0.84 | KMT2A (0.48) | FAAH | |
| SCHEMBL16673142 | 0.81 | SMN1; SMN2 (0.48) | FAAH | |
| SCHEMBL864449 | 0.80 | FAAH (0.54) | FAAHTRPA1MAPTRXFP1HDAC1 | |
| SCHEMBL23176819 | 0.78 | S1PR2 (0.50) | FAAHTRPA1MAPTRXFP1ALOX5 | |
| SCHEMBL6190476 | 0.78 | KMT2A (0.48) | FAAHMAPT | |
| SCHEMBL16149006 | 0.78 | KMT2A (0.48) | FAAHMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835240-B1 | MATRIX METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 2000-11-02 | — | — | EP | disclosed |
| US-5917090-A | INHIBIT TUMOR NECROSIS FACTOR; ANTIARTHRITIC AGENTS | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 1999-06-29 | — | — | US | disclosed |
| EP-0835240-A1 | MATRIX METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-04-15 | — | — | EP | disclosed |
| WO-1997002239-A1 | MATRIX METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-01-23 | — | — | WO | disclosed |