Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.72 |
| ▸ | DRD3 | P35462 | 10/20 | 0.72 |
| ▸ | DRD4 | P21917 | 4/20 | 0.60 |
| ▸ | HTR1D | P28221 | 2/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7333838 | 0.99 | DRD2 (0.70) | DRD2DRD3DRD4HTR1DGRIN2B | |
| SCHEMBL14847040 | 0.92 | DRD2 (0.71) | DRD2DRD3DRD4HTR1DHTR1B | |
| SCHEMBL7327300 | 0.92 | DRD2 (0.71) | DRD2DRD3DRD4HTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL7327372 | 0.90 | DRD2 (0.69) | DRD2DRD3DRD4HTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL7334497 | 0.90 | DRD2 (0.69) | DRD2DRD3DRD4HTR1DHTR1B | |
| SCHEMBL7332696 | 0.86 | DRD2 (0.66) | DRD2DRD3DRD4HTR1DGRIN2B | |
| Hydrochloric Acid SCHEMBL7333877 | 0.85 | DRD2 (0.64) | DRD2DRD3DRD4HTR1DGRIN2B | |
| SCHEMBL7325905 | 0.83 | GRIN2B (0.70) | DRD2DRD3GRIN2BSIGMAR1 | |
| SCHEMBL7328248 | 0.82 | GRIN2B (0.70) | DRD2DRD3GRIN2BSIGMAR1 | |
| Hydrochloric Acid SCHEMBL7336883 | 0.82 | GRIN2B (0.68) | DRD2DRD3GRIN2BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0402923-A2 | 2,5-Diaminotetralines, process for their preparation and their use as medicine | BOEHRINGER INGELHEIM KG (DE) | 1990-12-19 | — | — | EP | disclosed |