Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.42 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.42 |
| ▸ | ITGAL | P20701 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | IDUA | P35475 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CAD | P27708 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326331 | 1.00 | ITGB1 (0.42) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL7327644 | 1.00 | ITGB1 (0.42) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL3508648 | 0.81 | ALOX5 (0.42) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL3508647 | 0.81 | ALOX5 (0.42) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL27546984 | 0.80 | ITGB1 (0.39) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL27546983 | 0.80 | ITGB1 (0.39) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL7512566 | 0.79 | KMT2A (0.43) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL7449138 | 0.79 | KMT2A (0.43) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL9745679 | 0.79 | KMT2A (0.43) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL9744632 | 0.79 | KMT2A (0.43) | ITGB1ITGA5ITGB3ITGB2ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151497-A | Central nervous system disorders, antidepressants, epilepsy and cognition activators | JAPAN TOBACCO INC. (JP) | 1992-09-29 | — | — | US | disclosed |
| EP-0384380-A2 | Novel peptide derivatives and their pharmaceutical use | JAPAN TOBACCO INC. (JP) | 1990-08-29 | — | — | EP | disclosed |