Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | ORAI1 | Q96D31 | 3/20 | 0.39 |
| ▸ | TRPC3 | Q13507 | 3/20 | 0.39 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.39 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7383391 | 0.82 | ALDH1A1 (0.49) | TP53MAPTKDM4ETHRBPTGS2 | |
| SCHEMBL7319471 | 0.77 | ORAI1 (0.52) | TP53MAPTGAAKDM4EL3MBTL1 | |
| SCHEMBL7391522 | 0.75 | ALDH1A1 (0.45) | TP53MAPTKDM4EPTGS2ALDH1A1 | |
| SCHEMBL7313393 | 0.74 | ORAI1 (0.46) | TP53MAPTGAAKDM4ETHRB | |
| SCHEMBL7546922 | 0.74 | MAPT (0.48) | MAPTGAAKDM4ETHRBPTGS2 | |
| SCHEMBL7382276 | 0.73 | ORAI1 (0.36) | TP53MAPTKDM4EL3MBTL1THRB | |
| SCHEMBL25012415 | 0.72 | CFTR (0.48) | MAPTGAACFTRKDM4EL3MBTL1 | |
| SCHEMBL5097191 | 0.72 | KLKB1 (0.45) | MAPTKDM4EL3MBTL1PTGS2 | |
| SCHEMBL12632739 | 0.72 | MYC (0.52) | TP53MAPTKDM4EL3MBTL1THRB | |
| SCHEMBL7319585 | 0.71 | KDM4E (0.48) | MAPTGAAKDM4EL3MBTL1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010044445-A1 | AZOLE INHIBITORS OF CYTOKINE PRODUCTION | ABBOTT LABORATORIES | 2001-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010044445-A1 | AZOLE INHIBITORS OF CYTOKINE PRODUCTION | IL5, IL2, IL4 | TP53 1903/4885MAPT 2674/4885GAA 2993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.