Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.44 |
| ▸ | DRD3 | P35462 | 8/20 | 0.44 |
| ▸ | HTR7 | P34969 | 4/20 | 0.44 |
| ▸ | DRD4 | P21917 | 4/20 | 0.43 |
| ▸ | DRD1 | P21728 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7327193 | 0.94 | BCHE (0.44) | DRD2DRD3HTR7DRD4 | |
| SCHEMBL7331942 | 0.93 | DRD2 (0.43) | DRD2DRD3HTR7DRD4 | |
| SCHEMBL7327537 | 0.93 | DRD2 (0.45) | DRD2DRD3HTR7DRD4 | |
| SCHEMBL7327744 | 0.90 | DRD2 (0.45) | DRD2DRD3HTR7DRD4DRD1 | |
| SCHEMBL7327507 | 0.88 | CHRNA7 (0.42) | DRD2DRD3HTR7HTR1A | |
| SCHEMBL7328262 | 0.84 | BCHE (0.43) | DRD2DRD3HTR7HTR1A | |
| SCHEMBL7330583 | 0.83 | BCHE (0.41) | DRD2DRD3HTR7HTR1A | |
| SCHEMBL7334570 | 0.83 | BCHE (0.40) | DRD2DRD3 | |
| SCHEMBL7328342 | 0.82 | HTR1A (0.41) | DRD2DRD3HTR7HTR1A | |
| SCHEMBL7328955 | 0.80 | DRD2 (0.64) | DRD2DRD3HTR7DRD4DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0402923-A2 | 2,5-Diaminotetralines, process for their preparation and their use as medicine | BOEHRINGER INGELHEIM KG (DE) | 1990-12-19 | — | — | EP | disclosed |