⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7028206 | 0.79 | — | — | |
| SCHEMBL4555703 | 0.77 | — | — | |
| SCHEMBL1239517 | 0.74 | HTR3E (0.30) | — | |
| SCHEMBL589950 | 0.72 | — | — | |
| SCHEMBL29939400 | 0.71 | — | — | |
| SCHEMBL7348642 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL1071446 | 0.68 | — | — | |
| SCHEMBL28101541 | 0.67 | NCF1 (0.39) | — | |
| Acetamide SCHEMBL27716284 | 0.66 | — | — | |
| SCHEMBL1648888 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364844-A | Hypotensive agents | SANKYO COMPANY, LIMITED (JP) | 1994-11-15 | — | — | US | disclosed |
| EP-0326364-B1 | Renin inhibitory oligopeptides, their preparation and use | SANKYO CO (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0326364-A2 | Renin inhibitory oligopeptides, their preparation and use | Sankyo Company Limited (JP) | 1989-08-02 | — | — | EP | disclosed |