Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 10/20 | 0.49 |
| ▸ | ITGAV | P06756 | 9/20 | 0.49 |
| ▸ | ITGA5 | P08648 | 9/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 7/20 | 0.49 |
| ▸ | MDM4 | O15151 | 4/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GPR139 | Q6DWJ6 | 3/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.39 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.39 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.39 |
| ▸ | ITGA8 | P53708 | 1/20 | 0.39 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328446 | 0.95 | ITGB3 (0.53) | ITGB3ITGB1ITGAVITGA5MDM2 | |
| Trifluoroacetic Acid SCHEMBL7329305 | 0.91 | ITGB3 (0.43) | ITGB3ITGB1ITGAVITGA5MDM2 | |
| SCHEMBL7315631 | 0.87 | ITGB3 (0.50) | ITGB3ITGB1ITGAVITGA5MDM2 | |
| SCHEMBL7322874 | 0.85 | ITGB3 (0.47) | ITGB3ITGB1ITGAVITGA5MDM2 | |
| SCHEMBL6783208 | 0.82 | ITGB3 (0.46) | ITGB3ITGB1ITGAVITGA5MDM2 | |
| SCHEMBL18269210 | 0.81 | ITGB3 (0.48) | ITGB3ITGB1ITGAVITGA5MDM2 | |
| SCHEMBL18271386 | 0.81 | ITGB3 (0.49) | ITGB3ITGB1ITGAVITGA5MDM2 | |
| SCHEMBL30083944 | 0.81 | ITGB3 (0.51) | ITGB3ITGB1ITGAVITGA5MDM2 | |
| Trifluoroacetic Acid SCHEMBL3835291 | 0.81 | ITGB3 (0.51) | ITGB3ITGB1ITGAVITGA5MDM2 | |
| Trifluoroacetic Acid SCHEMBL7321339 | 0.80 | CTSB (0.41) | ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0584066-A4 | ANTI-THROMBOTIC PEPTIDE AND PSEUDOPEPTIDE DERIVATIVES. | RHONE POULENC RORER INT (US) | 1994-10-12 | — | — | EP | claimed |
| EP-0584066-A1 | ANTI-THROMBOTIC PEPTIDE AND PSEUDOPEPTIDE DERIVATIVES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1994-03-02 | — | — | EP | claimed |
| WO-1992018117-A1 | ANTI-THROMBOTIC PEPTIDE AND PSEUDOPEPTIDE DERIVATIVES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS), INC. (US) | 1992-10-29 | — | — | WO | claimed |
| EP-0584066-A4 | ANTI-THROMBOTIC PEPTIDE AND PSEUDOPEPTIDE DERIVATIVES. | RHONE POULENC RORER INT (US) | 1994-10-12 | — | — | EP | disclosed |
| EP-0584066-A1 | ANTI-THROMBOTIC PEPTIDE AND PSEUDOPEPTIDE DERIVATIVES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1994-03-02 | — | — | EP | disclosed |
| WO-1992018117-A1 | ANTI-THROMBOTIC PEPTIDE AND PSEUDOPEPTIDE DERIVATIVES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS), INC. (US) | 1992-10-29 | — | — | WO | disclosed |