Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 13/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22121922 | 0.85 | PTGS2 (0.52) | PTGS2PTGS1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7205947 | 0.84 | PTGS1 (0.58) | PTGS2PTGS1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7327229 | 0.84 | PTGS2 (0.53) | PTGS2PTGS1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL18865753 | 0.84 | PTGS2 (0.49) | PTGS2PTGS1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL27031423 | 0.83 | CASR (0.52) | PTGS2PTGS1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL27140109 | 0.83 | CASR (0.52) | PTGS2PTGS1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7322949 | 0.82 | PTGS2 (0.51) | PTGS2PTGS1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29140759 | 0.82 | PTGS2 (0.53) | PTGS2PTGS1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29140716 | 0.82 | PTGS2 (0.49) | PTGS2PTGS1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL22122093 | 0.81 | PTGS2 (0.52) | PTGS2PTGS1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010044445-A1 | AZOLE INHIBITORS OF CYTOKINE PRODUCTION | ABBOTT LABORATORIES | 2001-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010044445-A1 | AZOLE INHIBITORS OF CYTOKINE PRODUCTION | IL5, IL2, IL4 | PTGS2 158/4885PTGS1 197/4885CYP1A2 42/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.