Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326708 | 1.00 | SLC6A9 (0.42) | SLC6A9OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL8651682 | 1.00 | SLC6A9 (0.42) | SLC6A9OPRM1OPRD1OPRK1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8655771 | 0.99 | SLC6A9 (0.42) | SLC6A9OPRM1OPRD1OPRK1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8654170 | 0.94 | OPRM1 (0.43) | SLC6A9OPRM1OPRD1OPRK1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7335458 | 0.94 | OPRM1 (0.43) | SLC6A9OPRM1OPRD1OPRK1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7335461 | 0.94 | OPRM1 (0.43) | SLC6A9OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL7331363 | 0.86 | NPY5R (0.39) | SLC6A9OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL7328323 | 0.86 | BCHE (0.43) | SLC6A9 | |
| SCHEMBL7326833 | 0.86 | BCHE (0.43) | SLC6A9 | |
| Hydrochloric Acid SCHEMBL8652261 | 0.85 | NPY5R (0.39) | SLC6A9OPRM1OPRD1OPRK1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711271-A1 | AMINOINDANES AND RELATED COMPOUNDS USEFUL AS CALCIUM-CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004027-A1 | AMINOINDANES AND RELATED COMPOUNDS USEFUL AS CALCIUM-CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-02-09 | — | — | WO | disclosed |